Fig. 8From: Targeting Mitochondrial Complex I Deficiency in MPP+/MPTP-induced Parkinson’s Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 GeneNDI1 can inhibit inflammatory response (decrease the number of astrocytes and microglia) and maintain number of neurons in SN of MPTP-induced PD mouse model. A, B, C: Astrocytes (GFAP-positive, cytoplasm), microglia (Iba-1-positive, cytoplasm), neurons (NeuN-positive, nucleus) were detected by immunohistochemical staining with GFAP antibody, Iba-1 antibody and NeuN antibody, respectively. (Scale bar: 100 μm). D, E, F: Statistical analysis of the proportion of astrocytes (GFAP-positive), microglia (Iba-1 positive), neurons (NeuN-positive). ns: no significant difference, *: P < 0.05, **: P < 0.01, ***: P < 0.001Back to article page