Fig. 2

Comparison of oncolytic efficiency and replication of PD-H and PD-SK in colorectal cancer cell lines. (A) Cell viability. The colorectal cancer cell lines Colo320, Colo205, DLD-1, CaCo-2, CT-26, Colon-26 and Colo680H were infected with PD-H and PD-SK at indicated MOIs; cell viability was measured 24 h and 48 h after infection. Shown are mean values ± SEM. Significance, * p < 0.05, ** p < 0.01; *** p < 0.001; **** p < 0.0001. (B) Virus titer. Cells were infected with MOI 1; virus titer was determined 48 h after infection by plaque assay. Shown are mean values ± SEM; Significance, * p < 0.05; ** p < 0.01